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Graduate College of Biomedical Sciences

Pechnick Lab

The research in my laboratory is focused on three aspects of neuropsychopharmacology: using animals models to understand the causes of and to develop new potential treatments for various forms of mental illness; utilizing both in vivo and in vitro approaches to study the neuropharmacology of drugs of abuse; and defining the role of hippocampal neurogenesis in health and disease states. Primary goals include: characterizing the role of developmental insults (prenatal, neonatal and adolescent) in producing neuropsychiatric disorders; defining the involvement of cytokines and stress in neurogenesis and depression; understanding the role of neurogenesis in post-chemotherapy-induced cognitive dysfunction. Graph showing altered spatial memory treatment with chemotherapeutic drug methotrexate Comparative pictures of cells