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Maria Lambros, BS, MS, PhD

Associate Professor of Pharmaceutical Sciences

College of Pharmacy

E-Mail: mlambros@westernu.edu

Phone: 909-469-5583

Education


Ph.D. 1991
University of Minnesota, Minneapolis, MN
 

MS 1983
Univiversity of Cincinnati, Cincinnati, OH
 

BS 1981
National University of Athens, Greece

 

Research Interest

Physicochemical evaluation and formulation of pharmaceuticals, drug delivery systems including aerosols and dermatologicals. Studies on the interaction of proteins with lipid membranes.

Publications

Lambros, M, Huang, Y, Mulamalla, HC, Patent “Targeted Liposomes in Cancer Therapy” Patent no 9808425 https://patents.google.com/patent/US9808425B2/en?oq=US9808425

Fei Q, Kent D, Botello-Smith WM, Nur F, Nur S, Alsamarah A, Chatterjee P, Lambros M, Luo Y. Molecular Mechanism of Resveratrol’s Lipid Membrane Protection. Scientific Reports. 2018;8   http://dx.doi:10.1038/s41598-017-18943-1

Moreno, J. A., Sanchez, A., Hoffman, R. M., Nur, S., Lambros, M. P. Fluorescent Orthotopic Mouse Model of Pancreatic Cancer. J. Vis. Exp. (115), e54337, 2016,doi:10.3791/54337

Lambros, M. P., M. K. DeSalvo, H. C. Mulamalla, J. Moreno,and L. Kondapalli. "Genome wide expression after different doses of irradiation of a three-dimensional (3D) model of oral mucosal" Genomics Data, 7: 137-139, 2016,  doi:10.1016/j.gdata.2015.12.013

Lambros, MP, DeSalvo, MK, Moreno, J, Mulamalla, HC, Kondapalli, L., “Transcriptional Profiling of Radiation Damage and Preventive Treatments In a 3-Dimensional (3D) Human Cell Culture Model of Oral Mucositis”, Genomics Data, 6:40-43, 2015, http://dx.doi.org/10.1016/j.gdata.2015.07.029

Lambros, MP, Kondapalli, L, Parsa, C, Mulamalla, HC, Orlando, R, Pon, D, Huang, Chow, MSS., “Molecular Signatures in the Prevention of Radiation Damage by the Synergistic Effect of N-Acetyl Cysteine and Qingre Liyan Decoction, a Traditional Chinese Medicine, Using a 3-Dimentional Cell Culture Model of Oral Mucositis”, Evidence-Based Complementary and Alternative Medicine, Article ID 425760, 2015, http://dx.doi.org/10.1155/2015/425760

Lambros, MP, Beringer, P, Wong-Beringer, A., “Nebulizer Choice Affects the Airway Targeting of Amphotericin B Lipid Complex Aerosols”, J Pharm Tec. 29:199-205, 2013

Lewerenz J, Hewett SJ, Huang Y, Lambros M, Gout PW, Kalivas PW, Massie A, Smolders I, Methner A, Pergande M, Smith SB, Ganapathy V, Maher P. The Cystine/Glutamate Antiporter System x(c)(-) in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities. . Antioxid Redox Signal, 2012 Aug 3. [Epub ahead of print] PubMed PMID: 22667998.

Lambros, MP., Parsa, C., Mulamalla, HC., Orlando, R., Lau, B., Pon, D., Chow, M., “Identifying Cell and Molecular Stress After Irradiation in a Three Dimensional (3-D) Model of Oral Mucositis” Biochemical and Biophysica Research Communications, 405:102-106, 2011.

Wong Beringer, A., Polikandritou Lambros, M., Beringer, P., Johnson D.L., “Suitability of Caspofungin for Prevention of Pulmonary Aspergillosis: Physicochemical Profiling and Nebulizer Choice” Chest, 128:3711-3716, 2005.

Polikandritou Lambros, M. and Y. E. Rahman "Effect of A Polypeptide on Model Lipid Membranes" Chemistry and Physics of Lipids 131: 63-69, 2004.

Polikandritou Lambros, M. Abbas, S.A., Dunn T., Raja, T., and Pento, "Targeting Hepatocytes with Liposomal Interferon alpha: "Effect on Metallothionein Gene Induction" Research Communications in Molecular Pathology and Pharmacology, 112:50-58, 2002.

Abang, A. M., Abbas, S.A., Pham, T., Polikandritou Lambros, M. "A New HPLC Method for Fludarabine and Fludarabine Phosphate Compounded in Liposomes" International Journal of Pharmaceutical Compounding, 5:320-322, 2001

Polikandritou Lambros, M., Schafer, F., Blackstock, R., and Murphy, J. W., "Liposomes, a Potential Immunoadjuvant and Carrier for a Cryptococcal Vaccine" J. Pharm. Sci., 87:1144-1148, 1998.

Polikandritou Lambros, M., Sheu, Y. L., and Pereira, H. A., "Interaction of a Synthetic Peptide Based on the Neutrophil-Derived Antimicrobial Protein CAP-37 with Dipalmitoyl-Phosphatidylcholine Membranes", Biochim. Biophys. Acta, 1329:285-290, 1997