Education

2006 Ph.D., University of Michigan School of Dentistry, Ann Arbor, MI

2000 D.D.S., University of Michigan School of Dentistry, Ann Arbor, MI

1996 B.S., Biology, Northern Michigan University, Marquette, MI

Selected Honors

Individual Mentored Clinical Scientist Development Award NIH/NIDCR 2003-2008

AADR/Pfizer Hatton Award, 2005 American Association for Dental Research meeting in Baltimore, Maryland.

The Robert Gorlin Award, 2005 American Academy of Oral and Maxillofacial Pathology Meeting in Destin, Florida

The Dr. Dominic D. Dziewiakowski Award For Excellence in Research, 2005.

Glenn Foundation for Medical Research/American Federation for Aging Research (AFAR) Scholarship for Research in the Biology of Aging 1999

Research Interests

The primary focus of Dr Henson s research is to identify the molecular events that predict the biological behavior of individual head and neck squamous cell carcinomas. Specifically, Dr. Henson has been investigating the novel role of Galanin and the Galanin Receptors in tumor development and progression. His studies support further investigation of these proteins as objective markers and specific treatment targets to reduce the morbidity of oropharyngeal cancers. As biomedical research continues its trend toward a translational research objective, Dr. Henson s research intends to partner basic science knowledge with practical clinical application. Recently, he was a member of a team pioneering the use of salivary biomarkers for the early detection of head and neck tumors.

Selected Publications

Arellano-Garcia, ME, Hu S, Wang J, Henson BS, Zhou H, Chia D and Wong DT. Multiplexed immunobead-based assay for detection of oral cancer protein biomarkers in saliva. Oral Diseases. 2008 Nov;14(8):705-12.

Liu H-L, Henson BS, Zhou Y, D Silva NJ and Mistretta CM. Fungiform papilla pattern: EGF regulates inter-papilla lingual epithelium and decreases papilla number. Dev Dyn. 2008 Sep;237(9):2378-93.

Hu Z, Zimmermann BG, Zhou H, Wang J, Henson BS, Yu W, Elashoff D, Krupp G and Wong DT. Exon level expression profiling: a comprehensive transcriptome analysis for body fluids. Clin Chem. 2008 May;54(5):824-32

Denny P, Hagen FK, Hardt M, Liao L, Yan W, Arellanno M, Bassilian S, Bedi GS, Boontheung P, Cociorva D, Delahunty CM, Denny T, Dunsmore J, Faull KF, Gilligan J, Gonzalez-Begne M, Halgand F, Hall SC, Han X, Henson B, et. al. The Proteomes of Human Parotid and Submandibular/Sublingual Gland Salivas Collected as the Ductal Secretions. J Proteome Res. 2008 Mar 25.

Henson BS, Carey TE, D Silva NJ. An optimized orthotopic floor-of-the-mouth cancer model allows for localized placement of human squamous cell carcinoma cells. Journal of Oral Pathology and Medicine. 2007 Jul;36(6):363-70.

Zhang ZC, Mitra R, Henson BS, Datta N, McCauley L, Kumar P, J. Lee S-J, Carey TE and D Sliva NJ. Rap1GAP inhibits tumor growth in oropharynegeal squamous cell carcinoma. American Journal of Pathology. 2007 Feb;168(2):585-96.

Wang SJ, Wolter KG, Henson BS, Wang S, Griffith KA, Carey TE, Kumar B, Chen J, Bradford CR and D Silva NJ. A novel small molecule inhibitor of Bcl-X_L inhibits growth of human head and neck squamous cell carcinoma in vivo. Neoplasia. 2006 March;8(3):163-172.

Henson BS, Neubig R, Jang I, Ogawa T, Zhang ZC, Carey TE, D Silva NJ. Galanin Receptor 1 has anti-proliferative effects in oral squamous cell carcinoma. Journal of Biological Chemistry. 2005 Jun 17;280(24):22564-22571.