Zhongting Hu - Assistant Professor of Anatomy - COMP - Western University of Health Sciences

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Zhongting Hu - Assistant Professor of Anatomy

Background

Education
Shanghai Medical University, Shanghai, China B.S. Medicine 1980-1985
Graduate School of Shanghai Medical University M.S. Neurobiology 1985-1988
Kyoto Prefectural University of Medicine, Japan Ph.D. Neurobiology 1993-1998
University of California at Los Angeles, California Postdoctoral Molecular Biology 1998-2002

Positions and Employment

1980-1985: Medical student in Shanghai Medical University, Shanghai, P.R. China
1985-1988: Masters student, Neurobiology Department, Shanghai Medical University, Shanghai, China
1988-1993: Assistant Professor, Neurobiology Department, Shanghai Medical University, Shanghai, China
1993-1998: Ph.D. student, Neurobiology Department, Kyoto Prefectural University of Medicine, Japan
1998-2002: Postdoctoral fellow, Department of Psychiatry, School of Medicine, Los Angeles, CA
2002-2006: Senior Scientist, Ambion Inc, Austin, Texas
2006- : Assistant Professor, Dept of Anat, College of Osteopathic, Western University, Los Angeles, CA

Other Experience and Professional Memberships

1992-1993: Director of Histological Division, Chinese State Lab of Neurobiology at Shanghai
1996-; Membership of Society of Neuroscience

Honors

1994-1995: Excellent Research Paper awarded from China Association of Anatomy
1997-1998: Japanese Government Scholarship for Excellent Ph.D. student
1998-1999: UCLA Stein-Oppenheimer Award for Brain Developmental Study

Selected Peer-Reviewed Publications (In Chronological Order)

Zhongting Hu, Kazunari Yuri, Tomoki Ichikawa and Mitsuhiro Kawata (1996) Exposure of postnatal rats to glucocorticoids suppresses the development of choline acetyltransferase-immunoreactive neurons: role of adrenal steroids in the development of forebrain cholinergic neurons. Journal of Chemical Neuroanatomy 10:1-10.

Zhongting Hu, David Visser, R. Jeroen Pasterkamp, Masafumi Morimoto and Mitsuhiro Kawata (1996) The change of glucocorticoid receptor immunoreactivity in the rat forebrain following short-term and long-term adrenalectomy. Brain Research 729:216-222.

Zhongting Hu, Kazunari Yuri, Hitoshi Ozawa, Haiping Lu and Mitsuhiro Kawata (1997) The in vivo time course for elimination of adrenalectomy-induced apoptotic profiles from the granule cell layer of the rat hippocampus. Journal of Neuroscience 17:3981-3989.

Zhongting Hu, Kazunari Yuri, Masafumi Morimoto and Mitsuhiro Kawata (1997) Chronic loss of corticosterone after adrenalectomy down-regulates the expression of glucocorticoid receptor mRNA in rat forebrain. European Journal of Neuroscience 9:1778-1783.

Zhongting Hu, Kazunari Yuri, Hitoshi Ozawa, Haiping Lu, Yimu Yang and Mitsuhiro Kawata (1997) ADX-induced cell death is predicated on the loss of the glucocorticoid receptor immunoreactivity in the hippocampal granule cell layer. Brain Research 778:293-301.

Zhongting Hu, Takao Ito, Kazunari Yuri, Cangxia Xie, Hitoshi Ozawa and Mitsuhiro Kawata (1998) The course of morphological changes and DNA degradation during the degeneration of castration-induced apoptotic prostate cells. Cell and Tissue Research 294:153-160.

Zhongting Hu, Kazunari Yuri, and Mitsuhiro Kawata (1999) Chronic lack of endogenous glucocorticoids down-regulates glucocorticoid receptor levels in the rat forebrain. Neuroscience 90:1185-1195.

Zhongting Hu, Vincent Lelievre, Alan Chao, Xinrong Zhou and James A. Waschek (2000) Characterization and mRNA distribution of a cloned pituitary adenylyl cyclase-activating polypeptide type I receptor in the Xenopus laevis brain. Endocrinology 141:657-665.

Zhongting Hu, Vincent Lelievre, Jimmy Tang, Jennfier W. Cheng and James A. Waschek (2000) Molecular cloning of growth hormone-releasing hormone/pituitary adenylyl cyclase-activating polypeptide in the Xenopus laevis: Brain distribution and regulation after castration. Endocrinology 141:3366-3376.

Zhongting Hu, Vincent Lelierve, Williams I. Rodriguez, Jimmy Tam, Jennifer W. Cheng, Susann Cohen- Cory and James A. Waschek (2001) Embryonic expression of pituitary adenylyl cyclase-activating polypeptide and its selective type I receptor gene in the frog Xenopus laevis neural tube. Journal of Comparative Neurology 441:266-275.

Zhongting Hu, Vincent Lelievre, Williams I. Rodriguez, Jennifer W. Cheng and James A. Waschek (2002) Comparative distributions of pituitary adenylyl cyclase activating polypeptide and its selective type I receptor mRNA in the frog (Xenopus laevis) brain.Regulatory Peptides 109:15-26.

Mitsuhiro Kawata, Kazunari Yuri, Zhongting Hu and Maki Yoshida (1998) Steroid hormones and their receptors in the brain. Journal Steroid Biochemical Molecular Biology 65:273-280.

Xinrong Zhou, Veasna Ma, Zhongting Hu, Alan Chao and James A. Waschek (1999) Axotomy-induced changes in pituitary adenylyl cyclase activating polypeptide and receptor gene expression in the rat facial motor nucleus. Journal of Neuroscience Research 57:953-961.

Vincent Lelierve, Nicolas Pineau, Zhongting Hu, Ji-Yun Byun, Yevgeniya Ioffe, Jean-Marc Muller, and James A. Waschek (2001) Proliferative actions of natriuretic peptides on neuroblastoma cells: involvement of guanylyl cyclase and non-guanylyl cyclase pathways. Journal of Biological Chemistry 276:43668-43676.

Vincert lelierve, Zhongting Hu, Ji-Yun Byun, Yevgeniya Ioffe, James A. Waschek (2002) FGF-2 converts PACAP growth action on embryonic hindbrain precursors from stimulation to inhibition. J. Neuroscience Research 67:566-573.

James Waschek, Dicicco-Bloom EM, Vincent Lelievre, Xingrong Zhou, Zhongting Hu (2002) PACAP action in nervous system development, regeneration, and neuroblastoma cell proliferation. Ann N Y Acad Sci 921:129-36.

Brian D. Armstrong, Zhongting Hu, Miya Yamamoto, Williams I. Rodriguez, Jennifer Cheng, Jimmy Tam, Rosa P. Gomariz, Paul H. Patterson, James A. Waschek (2003) Lymphocyte Regulation of Neuropeptide Gene Expression Following Neuronal Injury. J. Neurosci. Res. (In Press).

Colwell CS, Michel S, Itri J, Rodriguez W, Tam J, Lelievre V, Hu Z, Liu X, Waschek JA (2004) Disrupted Circadian Rhythms in VIP and PHI Deficient Mice. J Physiology 74:240-247.
Armstrong BD, Zhongting Hu, Yamamoto M, Rodriguez WI, Cheng J, Lee M, Chhith S, Waschek JA. (2004) Induction of neuropeptide gene expression and blockade of retrograde transport in facial motor neurons following local peripheral nerve inflammation in severe combined immunodeficiency and BALB/C mice. Neuroscience 129:93-99.

Colwell CS, Rodriguez W, Lelievre V, Zhongting Hu, Waschek JA. (2004) Selective deficits in the circadian light response in mice lacking PACAP. Am J Physiol Regul Integr Comp Physiol 287:R1194-1201.

Research Support

1995-1996: Research Grant funded by Japanese Sasagawa Medical and Clinic Research Foundation
2000-2001: NIH Training Grant in Neural Repair Study

Patent Application

Zhongting Hu, Emily E. Zeriger, John D. Vincugierra, Leo Mendoza, Brittan L. Pasloske (2004) Non-embedded tissue microarray technology for protein and nucleic acid analyses (US Patent: 60/615,248 Pending)

Supplemental Materials

The Instrument and Detailed Experimental Procedure to Make Human Tissue Microarray.

Last Updated:05/27/2007

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