 Katherine Mitsouras - Assistant Professor of Biochemistry
| Background |
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Education
Postdoctoral Training 2001 - 2005 - department of human genetics, David Geffen School of Medicine, University of California Los Angeles. Area of research: assessing genome-wide gene expression changes in human brain tumors using microarrays, tissue specific detection of alternative splicing in both normal and tumor tissue via custom splice-detection microarray technology
Ph.D. 2001 - department of biological chemistry, David Geffen School of Medicine, University of California Los Angeles. Area of research: biochemical analysis of eukaryotic gene regulation, mechanisms of gene activation in the Epstein-Barr Virus lytic cycle
B.S (Honors) Biochemistry & Moelcular Biology, Brown University. Area of research: mechanisms of maternal mRNA localization in xenopus oocytes.
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| Courses Taught at Western University |
Biochemistry & Medical Genetics: Molecular & Cellular
Basis of Medicine (OMSI). Dr. Mitsouras is responsible for teaching the carbohydrate metabolism component of the first year course. Her lectures include regulation and integration of metabolic pathways as well as genetic diseases resulting in aberrant metabolism. She also lectures on emerging disciplines including pharmacogenomics, stem cell therapy and genetic testing. |
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| Prior Teaching Experience |
Summer 1998 Teaching Assistant: Eukaryotic Gene Expression Laboratory Course
Cold Spring Harbor Laboratory
Cold Spring Harbor, NY.
Spring 1998 Teaching Assistant: Introductory Biology
Department of Molecular, Cell and Developmental Biology
UCLA, Los Angeles, CA.
Spring 1997 Teaching Assistant: Human Biochemistry and Nutrition Laboratory
David Geffen School of Medicine
UCLA, Los Angeles, CA.
Spring 1994 Teaching Assistant: Introductory Biology
Department of Biochemistry
Brown University, Providence, RI.
1993-1994 Teaching Assistant: Inorganic Chemistry Laboratory
Department of Chemistry
Brown University, Providence, RI.
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| Selected Publications |
1. Rickabaugh T., Brown H., Wu T.T., Song M.J., Hwang S., Deng H., Mitsouras K., and Sun R. "Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 RTA Reactivates Murine Gammaherpesvirus-68." 2005. J. Virol. 79(5):3217-22.
2. Le K *., Mitsouras K.*, Roy M., Wang Q., Xu Q., Nelson S.F., and Lee C. "Detecting Tissue-Specific Regulation of Alternative Splicing as a Qualitative Change in Microarray Data." 2004. Nucl. Acids Res. 32(22):e180.
*Co-first authors, listed alphabetically
3. Mitsouras K., Wong B., Arayata C., Johnson R.C., and Carey M. "The DNA Architectural Protein HMGB1 Displays Two Distinct Modes of Action that Promote Enhanceosome Assembly." 2002. Mol. Cell. Biol. 22(12): 4390-401.
4. Johnson K., Mitsouras K. and Carey M. "Eukaryotic Transcription: the Core of Eukaryotic Gene Activation." 2001. Curr. Biol. 11(13): R510-13.
5. Ellwood K., Chi T. Huang W., Mitsouras K., and Carey M. "Cooperative Assembly of RNA Polymerase II Transcription Complexes." 1998. Cold Spring Harb. Symp. Quant. Biol. 63:253-61.
6. Ozer J., Mitsouras K., Zerby D., Carey M., and Lieberman P.M. "Transcription Factor IIA derepresses TATA-Binding Protein (TBP)-Associated Factor Inhibition of TBP-DNABinding."1998. J. Biol. Chem. 273(23):14293-300.
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