Graduate College of Biomedical Sciences

News and Events

GCBS Dean, Michel Baudry, PhD has recently published a paper in Scientific Reports

The laboratory of GCBS Dean Michel Baudry, PhD, just published a paper in Scientific Reports, which identifies a new link between calpain-2 activation and tau hyperphosphorylation/aggregation, one of the hallmarks of Alzheimer’s disease (AD) and chronic traumatic encephalopathy (CTE), which affects many athletes. This might open the way for new treatments for AD and CTE, a goal pursued by NeurAegis, the start-up company co-founded by several WesternU faculty members.

Wang, Y., Hall, R.A., Lee, M., Kamgar-parsi, A., Bi, X. and Baudry, M. The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau phosphorylation. Scientific Reports | 7: 11771 | DOI:10.1038/s41598-017-12236-3.

Dr. Christina Goode and Dr. Colleen Talbot presented at the Associate for Medical Education Conference in Helsinki, Finland

Dr. Christina Goode, Professor/Associate Dean of Academic Affairs in GCBS, gave the oral presentation, “A Mission-Driven Special Master’s Program Helps Increase Diversity in Professional Schools,” with collaborator Dr. Colleen Talbot, Professor of Physiology, COMP-Northwest, at the recent AMEE meeting (Association for Medical Education) in Helsinki. AMEE is a worldwide organization with members in 90 countries on five continents that promotes international excellence in education in the health care professions across the continuum of undergraduate, postgraduate and continuing education.

Professor, Q. Quinn Li, PhD. recently published in The Plant Journal

GCBS Professor Q. Quinn Li, PhD, with his student Juncheng Lin who worked on the project for a year here at WesternU, and collaborators, recently published a research paper in The Plant Journal (2017, 91:829–839) titled “Role of Cleavage and Polyadenylation Specificity Factor 100: Anchoring Poly(A) Sites and Terminating Transcription in Arabidopsis.” In this article, they extended the understanding of functions of the polyadenylation factor in terms of its far-reaching activity in transcription termination as well as alternative polyadenylation.

In another publication, Dr. Li and his students and associates studied the relationship between alternative splicing and alternative polyadenylation, two events that regulate gene expression during pre-mRNA processing. They demonstrated a competitive, sometime mutually exclusive, relationship for these two events, particularly for alternative poly(A) sites located in an intron. The article, “Interplay between Alternative Splicing and Alternative Polyadenylation Defines the Expression Outcome of the Plant Unique OXIDATIVE TOLERANT-6 Gene,” was published in Scientific Reports (2017, 7:2052).

Dr. Li also collaborated with bioinformatics scientists to study genome level distribution and potential functions of transposable elements in different ecotypes of the model plant Arabidopsis.  The results have been published in Scientific Reports (2017, 7:2634) entitled “Genome-Wide Comparative Analysis of Miniature Inverted Repeat Transposable Element in 19 Arabidopsis thaliana Accessions.”