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College of Osteopathic Medicine of the Pacific

Publications

See a complete PubMed list of publications by Miklos Peterfy, PhD.

Selected Key Publications

Sha H, Sun S, Francisco AB, Ehrhardt N, Xue Z, Liu L, Lawrence P, Mattijssen F, Guber RD, Panhwar MS, Brenna JT, Shi H, Xue B, , Kersten S, Bensadoun A, Peterfy M*, Long Q*, Qi L.* The ER-associated degradation adapter protein Sel1L regulates LPL secretion and lipid metabolism. Cell Metab. 2014;20(3):458-470. *co-senior authors. Link to publication

Mao HZ, Ehrhardt N, Bedoya C, Gomez JA, DeZwaan-McCabe D, Mungrue IN, Kaufman RJ, Rutkowski DT, Peterfy M. Lipase maturation factor 1 (lmf1) is induced by endoplasmic reticulum stress through activating transcription factor 6α (Atf6α) signaling. J Biol Chem. 2014;289(35):24417-24427. .Link to publication

Ehrhardt N, Bedoya C, Peterfy M. Embryonic viability, lipase deficiency, hypertriglyceridemia and neonatal lethality in a novel LMF1-deficient mouse model. Nutr Metab. 2014;11:37-45. Link to publication

Hosseini M, Ehrhardt N, Weissglas-Volkov D, Lai CM, Mao HZ, Liao JL, Nikkola E, Bensadoun A, Taskinen MR, Doolittle MH, Pajukanta P, Peterfy M. Transgenic expression and genetic variation of Lmf1 affect LPL activity in mice and humans. Arterioscler Thromb Vasc Biol. 2012;32(5):1204-1210. Link to publication

Peterfy M. Lipase maturation factor 1: a lipase chaperone involved in lipid metabolism. Biochim Biophys Acta. 2012;1821(5):790-794. Link to publication

Ben-Zeev O, Hosseini M, Lai CM, Ehrhardt N, Wong H, Cefalu AB, Noto D, Averna MR, Doolittle MH, Peterfy M. Lipase maturation factor 1 is required for endothelial lipase activity. J Lipid Res. 2011;52(6):1162-1169. Link to publication

Doolittle MH, Ehrhardt N, Peterfy M. Lipase maturation factor 1: structure and role in lipase folding and assembly. Curr Opin Lipidol. 2010;21(3):198-203.Link to publication

Davis RC, Castellani LW, Hosseini M, Ben-Zeev O, Mao HZ, Weinstein MM, Jung DY, Jun JY, Kim JK, Lusis AJ, Peterfy M. Early hepatic insulin resistance precedes the onset of diabetes in obese C57BLKS-db/db mice. Diabetes. 2010;59(7):1616-1625. Link to publication

Doolittle MH, Neher SB, Ben-Zeev O, Ling-Liao J, Gallagher CM, Hosseini M, Yin F, Wong H, Walter P, Peterfy M. Lipase maturation factor 1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum. J Biol Chem. 2009;284(48):33623-33633. Link to publication

Cefalu AB, Noto D, Arpi ML, Yin F, Spina R, Hilden H, Barbagallo CM, Carroccio A, Tarugi P, Squatrito S, Vigneri R, Taskinen M-R, Peterfy M, Averna MR. Novel LMF1 nonsense mutation in a patient with severe hypertriglyceridemia. J Clin Endocrin Metab. 2009;94(11):4584-4590. Link to publication

Yin F, Doolittle MH, Peterfy M. A quantitative assay measuring the function of lipase maturation factor 1. J Lipid Res. 2009;50(11):2265-2269. Link to publication

Peterfy M, Ben-Zeev O, Mao HZ, Weissglas-Volkov D, Aouizerat BE, Pullinger CR, Frost PH, Kane JP, Malloy MJ, Reue K, Pajukanta P, Doolittle MH. Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia. Nat Genet. 2007;39(12):1483-1487. Link to publication