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College of Pharmacy

MSPS Curriculum

To graduate, students are required to complete a minimum of 36 credit hours, which includes PHSC 6000 Graduate Seminar each semester (see the list of required courses listed below).

 

Required Courses

Subject/Course # Course Title Credit Hours
PHSC 5001 Principles of Biomedical Ethics 1.0
PHSC 5201 Pharmacokinetics, Pharmacodynamics & Pharmacogenomics 4.0
PHSC 5202 Pharmaceutics & Nanotechnology 4.0
PHSC 5500 Biostatistics 2.0
PHSC 6000 Graduate Seminar (4 semesters) 4 x 1.0
Various Course # Elective ≥ 1.0
PHSC 6999 Research & Thesis 20.0
  Total Required Credit  Hours: 36.0

For students enrolled prior to Fall 2019, PHSC 5101 Advanced Pharmaceutical Sciences I and PHSC 5102 Advanced Pharmaceutical Sciences II will be considered equivalent to PHSC 5201 Pharmacokinetics, Pharmacodynamics & Pharmacogenomics and PHSC 5202 Pharmaceutics & Nanotechnology, respectively. Additionally, PHSC 5500 Biostatistics is not required and all other course credits from previous catalogs will be honored. A minimum of 36 credit hours is required for graduation.

 

Elective Courses

Subject/Course # Course Title Credit Hours
PHSC 5111 Leadership Skills 1.0
PHSC 5112 Chemistry of Cosmetics 1.0
PHSC 6010 Pharmaceutical Analysis 2.0
PHSC 6020 Drug Discovery & Development 2.0
PHSC 6030 Biochemical Pharmacology 2.0
PHSC 6101 Novel Dosage Forms 3.0
PHSC 6102 Advanced Physical Pharmacy 3.0
PHSC 6103 Product Development 3.0
PHSC 6201 Advanced Pharmacokinetics 2.0
PHSC 6202 Computer-Aided Drug Design 3.0
PHSC 6300 Neuroscience 2.0
PHSC 6301 Neuropharmacology 2.0
PHSC 6302 Cardiovascular Physiology & Pharmacology 2.0
PHSC 6303 Cancer Biology, Therapy & Prevention 2.0
PHSC 6401 Immunology 2.0
PHSC 6403 Immunotherapies 2.0
PHSC 6500 Special Topics in Pharmaceutical Sciences 1.0 – 4.0
PHSC 6501 Recent Advances in Antimicrobials 2.0
PHSC 6701 Toxicology 1.0 – 2.0
PHSC 6901 Biochemistry & Molecular Biology Techniques 4.0

 

Continuous Registration

Subject/Course # Course Title Credit Hours
PHSC 6999A Research & Thesis Continuation* 0.5

* Students who do not complete elements of PHSC 6999 Research & Thesis in the 4th semester in which they are enrolled will continue their work in PHSC 6999A in the following semester(s).

 

Course Descriptions

All courses are awarded letter grades, except when indicated otherwise. Click here for a downloadable form containing all the information on this page for printout.

PHSC 5001 Principles of Biomedical Ethics (1 credit hour)

This course consists of three topics within modern biomedical ethics. First, the course will survey the various moral philosophies that are used in society as well as the biomedical enterprise. Second, the course will utilize a small group format to discuss medical scenarios to tease apart ethical approaches and the conflict between various ethical theories. Lastly, the course will continue in the small group format to discuss research ethics and use real cases to examine the role that ethics and ethical theories play in laboratory science. Students are also expected to explore their own ethical philosophy and articulate this philosophy in line with the traditional philosophies that will be discussed in class. Prerequisite: None

PHSC 5111 Leadership Skills (1 credit hour)

This is an exploratory course for student to find the leader within. There are on-line modules for reading, and self-assessments and projects for defining leadership. Discussion groups and guest speakers discuss leadership styles and roles in various settings. A second domain involves interaction with a leadership mentor. Lastly, students use reflections to define leadership and how they fit into leadership. Prerequisite: None

PHSC 5112 Chemistry of Cosmetic (1 credit hour, CR/NCR)

This course deals with formulation and applications of cosmetics and personal care products, including diverse topics such as skin, hair, bath products, sunscreens, perfumes and examines the microbiology and the preservation of cosmetics. The legislation of cosmetics will also briefly be examined. Prerequisite: None

PHSC 5201 Pharmacokinetics, Pharmacodynamics & Pharmacogenomics (4 credit hours)

This course exposes students to fundamental principles underlying pharmacokinetics, pharmacodynamics, and pharmacogenomics. Specifically students will learn about drug absorption, distribution, metabolism, and excretion (ADME), also known as “what the body does to a drug”. As well as generic mechanisms of drug action (dynamics), also known as “what the drug does to the body”. Lastly, the course will explore how ADME and dynamics are altered by the genomics of a patient. The topics in this course are to prepare students for advance study in the field of pharmaceutical sciences. Prerequisite: None

PHSC 5202 Pharmaceutics & Nanotechnology (4 credit hours)

Pharmaceutics and Nanotechnology will cover topics in physical pharmacy, pre-formulation, formulation of basic and advanced drug delivery system designs. Specific topics such as thermodynamics, drug stability and solubility, protein, peptide formulations, liposomal and polymer based nanotechnology products development will be covered extensively. Prerequisite: None

PHSC 5500 Biostatistics (2 credit hours)

This course is designed to provide fundamental principles of experimental design suitable for students in the pharmaceutical sciences.  The fundamentals of experimental design consist of formulating a testable hypothesis, developing various measurement strategies, ethical treatment of research subjects, validity, experimental and correlational research strategies, decision making in data collection and data interpretation. Prerequisite: None

PHSC 6000 Graduate Seminar (1 credit hour, CR/NCR)

Students enrolled in Graduate Seminar will present a journal article of their or their advisor’s choosing to the department once during the semester. The presentation follows the format of a one-hour plenary session at scientific meetings. To get credit for the course the students must evaluate each presentation. Students are expected to read the articles and be prepared to ask questions of the presenter. Prerequisite: None

PHSC 6010 Pharmaceutical Analysis (2 credit hours)

This course will provide the students the basic knowledge in both qualitative and quantitative pharmaceutical analysis, including UV, fluorescence, HPLC, NMR, LCMS and immunoassays. Prerequisite: None

PHSC 6020 Drug Discovery & Development (2 credit hours)

Drug Discovery & Development is designed to give students an overview of the drug discovery and development process. Students will have a foundational understanding of the goal of each stage and be familiar with the multidisciplinary approaches used throughout the process. Prerequisite: PHSC 6102 Pharmaceutics and Nanotechnology. Prerequisite: PHSC 5202 Pharmaceutics & Nanotechnology

PHSC 6030 Biochemical Pharmacology (2 credit hours)

Biochemical Pharmacology begins with an overview of basic cellular biology and biochemistry with a focus on pharmacologically important targets. The course then covers in detail the structure function of receptors, channels, transporters, and cellular enzymes including kinases and phosphatases.  Specific emphasis is placed on how these molecules are involved in disease states and how they can be manipulated pharmacologically to treat diseases. Prerequisite: PHSC 5201 Pharmacokinetics, Pharmacodynamics & Pharmacogenomics

PHSC 6101 Novel Dosage Forms (3 credit hours)

Drug formulation approaches have evolved over the years wherein conventional dosage forms, such as tablets and capsules, have expanded to include an array of novel formulations that are intended for transport of pharmaceutical compounds for desired therapeutic effect while maintaining safety profiles. This new generation of dosage forms is classified as Novel Drug Delivery Systems (NDDS) which includes formulations such as liposomes, microspheres, nanoparticles, self microemulsifying drug delivery systems (SMEDDS) and drug targeting etc. Students in this course will receive advanced information about NDDS through didactic, interactive lectures as well as hands-on laboratory exercises where they will learn to prepare new formulations and analyze their properties. Course assessments will be conducted via a combination of exams, term paper and written laboratory reports.  Prerequisite: PHSC 5202 Pharmaceutics & Nanotechnology

PHSC 6102 Advanced Physical Pharmacy (3 credit hours)

This course examines in depth topics in Physical Pharmacy which affect drug formulations and drug stability and educates the student about ways to troubleshoot common problems that arise when formulating drugs. Prerequisite: PHSC 5202 Pharmaceutics & Nanotechnology

PHSC 6103 Product Development (3 credit hours)

Pharmaceutical products range from conventional dosage forms such as tablets and capsules to more novel dosage forms such as liposomes and polymeric nanoparticles. Students in this laboratory based course will engage with the teaching faculty to identify products which will be developed within the Pharmaceutics labs. Thereafter, students will conduct feasibility and optimization studies to characterize the developed pharmaceutical product. No didactic instruction will be conducted however students must consult with the facilitator and teaching faculty at every step of the product development process. The course will culminate with the writing of a product development paper in the manuscript style of a peer reviewed journal (TBD) and an oral presentation of findings. Prerequisite: PHSC 6020 Drug Discovery & Development  

PHSC 6201 Advanced Pharmacokinetics (2 credit hours)

This course introduces the student to the kinetic processes by which drugs are absorbed, distributed and eliminated from the body, and to the mathematical methods of describing and quantitating these processes. These concepts will be used for the understanding of the factors which can influence the utilization profile of a drug. The design and implementation of pharmacokinetic studies and the analysis and interpretation of the data obtained will be emphasized. Prerequisite: PHSC 5201 Pharmacokinetics, Pharmacodynamics & Pharmacogenomics

PHSC 6202 Computer-Aided Drug Design (3 credit hours)

Contemporary drug design and discovery draws upon many disciplines that requires students having a broad knowledge of chemistry, physics, molecular biology, pharmacology, and computer technology. This advanced elective course is designed for graduate students in pharmaceutical sciences major to assemble the concepts and strategies on computer-aided drug design and discovery. Examples in structure-based design for a variety of diseases using pharmacophore modeling, QSAR, virtual screening, molecular dynamics and free energy calculations, ADMET property prediction will be introduced. While covering the fundamental concepts behind the methods, this course will provide a strong focus on the practical aspects of computer-assisted drug design using various software packages, such as MOE, OpenEye, AutoDock, NAMD, VMD. The hands-on training sections will be especially valuable to students who wish to use computer-based methods to enhance the productivity of their research or to acquire the skills in pharmaceutical industry R&D. Prerequisite: None

PHSC 6300 Neuroscience (2 credit hours)

This course is an overview of basic neuroscience principles starting with neuroanatomy, neurophysiology, and synaptic transmission.  The course then transitions to systems-based topics ranging from sensory perception, to endocrine and emotional processing circuitry. Prerequisite: None   

PHSC 6301 Neuropharmacology (2 credit hours)

This course is designed to enable students to understand how drugs alter neuronal communication and how these events lead to a change in behavior or alter the physiological state. Students in particular will learn about the role of different neurotransmitter/neuropeptide systems, their receptor types, drugs interacting with the neurotransmitter/neuropeptide systems, receptor/drug-mediated signal transduction, and the effects of drugs in addiction and other neuropsychiatric disorders. Prerequisite: PHSC 5201 Pharmacokinetics, Pharmacodynamics & Pharmacogenomics and PHSC 6300 Neuroscience

PHSC 6302 Cardiovascular Physiology & Pharmacology (2 credit hours)

Cardiovascular Physiology and Pharmacology is designed to give students a foundational understanding of concepts underlying normal cardiovascular function and how those mechanisms become altered in cardiovascular disease. The course will also cover cardiovascular pharmacology, with an emphasis on the latest research on drugs that are used to treat cardiovascular pathophysiology, presenting recent findings from primary literature. Prerequisite: PHSC 6030 Biochemical Pharmacology

PHSC 6303 Cancer Biology, Therapy & Prevention (2 credit hours)

Significant advances over the last decades have greatly increased the knowledge of cancer. It is now recognized that cancer is a collection of disorders with complex biology. Despite the complexity of cancer, basic, translational and clinical research has resulted in steady but incremental advances in prevention and therapy. This course will provide an introduction to cancer biology, therapy and prevention through interactive lectures and discussions. Particular interest will be paid to the molecular, cellular and genetic basis of disease, as well as the application in prevention, cancer chemotherapy, targeted therapy and immunotherapy, thus highlighting the challenges in this field of research and the possible avenues to explore. The objective of this course is designed to enable the students to understand basic principles of cancer biology and pharmacology and apply this knowledge into the practice of better drug development. Prerequisite: PHSC 6030 Biochemical Pharmacology

PHSC 6401 Immunology (2 credit hours)

This course is designed to enable the students to understand basic principles of immunology and apply this knowledge to better immunotherapy development and the importance of immunology in pharmaceutical sciences. Prerequisite: None

PHSC 6403 Immunotherapies (2 credit hours)

This course is designed to enable students to understand how the basic principles of immunology are used in immunotherapies as well as important issues that must be considered when discussing immunotherapies for patient treatment. Prerequisite: PHSC 6401 Immunology

PHSC 6500 Special Topics in Pharmaceutical Sciences (1-4 credit hours)

This course is designed to enable the students to understand advanced principles of their topic area through reading, analyzing and presenting research literature. Prerequisite: None

PHSC 6501 Recent Advances in Antimicrobials (2 credit hours)

Recent Advances in Antimicrobials does not have any pre- or co-requisites; however, it is designed for students who have a solid foundation in pharmacology. It covers diseases caused by viruses, bacteria, fungi, and parasites—often referred to as infectious diseases—as well as agents used to treat these diseases with an emphasis on recent advances in their discovery and development. Antimicrobial resistance is an important problem in antimicrobial chemotherapy and will be discussed throughout the course. Prerequisite: None

PHSC 6701 Toxicology (1-2 credit hours)

Toxicology is the study of poisons.  According to the alchemist Paracelsus, all substances are poisons and the dose differentiates a poison from a remedy.  This course will focus on the principles of toxicology and mechanisms of toxicity.  Examples of major toxic spills and human exposures will be discussed.  Case-based problems will be used to apply principles of toxicology and illustrate the major adverse health effects associated with environmental toxins. Prerequisite: None 

PHSC 6901 Biochemistry & Molecular Biology Techniques (4 credit hours)

This course is designed to introduce students to the key techniques used in the fields of biochemistry and molecular biology.  Students will use hands on experience of techniques and analysis of acquired results to learn about various experimental approaches. Prerequisite: None

PHSC 6999 Research & Thesis (1-9 credit hours, CR/NCR)

In this course, students are expected to conduct mentor-guided research based on a conceptualized project.  The mentor meets with the student on a regular basis to assess the progress of the laboratory research experiments and help guide the project.  The student is expected to conduct literature search and evaluation based on their experimental work.  Students will use the experimental findings to write a complete thesis. The course is a pass/fail course. Final assessment occurs when the student presents their thesis. Prerequisite: None

PHSC 6999A Research & Thesis Continuation (0.5 credit hour, CR/NCR)

PHSC 6999 Research & Thesis Continuation is a bridge between PHSC 6998 Research & Thesis and completion of the MSPS program. Students will take this course to satisfy enrollment requirements while completing their thesis work if it is not completed after two full years of PHSC 6998 Research & Thesis. Aside from the credit hours and specified time when this class is available, PHSC 6999 Research & Thesis Continuation is identical to PHSC 6998 Research & Thesis. Due to this identity students should refer to the PHSC 6998 Research & Thesis syllabus for further details. The course is a pass/fail course, but final assessment of the student occurs when the student presents their thesis. Prerequisite: PHSC 6999 Research & Thesis