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Research in the College of Dental Medicine

Bradley Henson, DDS

Bradley Henson, DDS, PhD Assistant Dean for Research and Biomedical
Sciences, Assistant Professor

Dr. Henson is the point-of-contact in the College of Dental Medicine
regarding matters related to research.

The primary focus of Dr. Henson’s research is to identify the
molecular events that predict the biological behavior of head and neck
squamous cell carcinomas. Over the course of his career he has
endeavored to meet this research objective on multiple fronts:
participating in a multidisciplinary parotid gland-sparing radiation
program, pioneering the use of salivary biomarkers for the early
detection of head and neck tumors, and deciphering the role of the
galanin receptors and small GTPase signaling in tumor development and
progression. As biomedical research continues its trend toward a
translational research objective, Dr. Henson’s research laboratory has
strived to partner basic science exploration with practical clinical
application. Consistent with this philosophy, Dr. Henson, in his role as
Assistant Dean for Research and Biomedical Sciences, facilitates student
participation in research, supports faculty research development, and
leads a team to integrate the basic and clinical sciences into an
exciting case-based approach to delivering the human systems courses.

Contact Bradley Henson, DDS, PhD, via email: 
bhenson@westernu.edu


Christopher Nosrat, DDS

Christopher Nosrat, DDS, PhD Professor, College of Dental Medicine and
Graduate College of Biomedical Sciences

Dr. Christopher Nosrat has several research interests; oral neurobiology, stem cell
biology and oral cancer. In 1995, he discovered that a protein (called
Brain-Derived Neurotrophic Factor) that has major fuctions in the
central nervous system, also plays a crucial role in connecting the
chemical sensors of the oral cavity (taste buds) to the nervous system.
His laboratory performed the pioneering biological tissue engineering
work with dental pulp stem cells, using models for spinal cord injury
(2001) and Parkinson’s disease (2004). His work with oral cancer has
also emphasized the role of chronic inflammation in development of HPV
(Human Papilloma Virus)-negative oral cancers. He has received several
major fundings from the National Institutes of Health (NIDCD, NIDCR) and
US Army. Complementing his research career, Dr. Nosrat has been a
teacher and educator for both dental and medical students, as well as
junior faculty, graduate students and postdoctoral fellows. He has been
directing and teaching courses in anatomy, histology, physiology,
embryology, neuroscience, and orthodontics, and has participated in
several preclinical/clinical courses in dentistry.

Contact Christopher Nosrat via email: 
cnosrat@westernu.edu


Irina Nosrat, DDS

Irina Nosrat, DDS Assistant Professor

Dr. Irina Nosrat’s current projects include exploration of animal models to study supertasting, and
bioinformatic studies on gene expression in the dental pulp.

Dr. Nosrat has studied the functional effects of proteins
produced in the dental pulp, and their possible life promoting
effect on dopaminergic nerve cells. She has shown that proteins secreted by dental pulp
cells promote the survival of embryonic dopaminergic neurons.

Contact Irina Nosrat via email: 
inosrat@westernu.edu