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Maria Lambros, BS, MS, PhD

Maria Lambros, BS, MS, PhD

Associate Professor of Pharmaceutical Sciences

College of Pharmacy

mlambros@westernu.edu

Phone: 909-469-5583

  • Education

    Ph.D. 1991
    University of Minnesota, Minneapolis, MN

    MS 1983
    Univiversity of Cincinnati, Cincinnati, OH

    BS 1981
    National University of Athens, Greece

  • Research Interest

    Physicochemical evaluation and formulation of pharmaceuticals, drug delivery systems including aerosols and dermatologicals. Studies on the interaction of proteins with lipid membranes.

  • Publications

    Lambros, M, Huang, Y, Mulamalla, HC, Patent “Targeted Liposomes in Cancer Therapy” Patent no 9808425 https://patents.google.com/patent/US9808425B2/en?oq=US9808425

    Fei Q, Kent D, Botello-Smith WM, Nur F, Nur S, Alsamarah A, Chatterjee P, Lambros M, Luo Y. Molecular Mechanism of Resveratrol’s Lipid Membrane Protection. Scientific Reports. 2018;8 http://dx.doi:10.1038/s41598-017-18943-1

    Moreno, J. A., Sanchez, A., Hoffman, R. M., Nur, S., Lambros, M. P. Fluorescent Orthotopic Mouse Model of Pancreatic Cancer.J. Vis. Exp.(115), e54337, 2016,doi:10.3791/54337

    Lambros, M. P., M. K. DeSalvo, H. C. Mulamalla, J. Moreno,and L. Kondapalli. "Genome wide expression after different doses of irradiation of a three-dimensional (3D) model of oral mucosal" Genomics Data, 7: 137-139, 2016, doi:10.1016/j.gdata.2015.12.013

    Lambros, MP, DeSalvo, MK, Moreno, J, Mulamalla, HC, Kondapalli, L., “Transcriptional Profiling of Radiation Damage and Preventive Treatments In a 3-Dimensional (3D) Human Cell Culture Model of Oral Mucositis”, Genomics Data, 6:40-43, 2015, http://dx.doi.org/10.1016/j.gdata.2015.07.029

    Lambros, MP, Kondapalli, L, Parsa, C, Mulamalla, HC, Orlando, R, Pon, D, Huang, Chow, MSS., “Molecular Signatures in the Prevention of Radiation Damage by the Synergistic Effect of N-Acetyl Cysteine and Qingre Liyan Decoction, a Traditional Chinese Medicine, Using a 3-Dimentional Cell Culture Model of Oral Mucositis”, Evidence-Based Complementary and Alternative Medicine, Article ID 425760, 2015, http://dx.doi.org/10.1155/2015/425760

    Lambros, MP, Beringer, P, Wong-Beringer, A., “Nebulizer Choice Affects the Airway Targeting of Amphotericin B Lipid Complex Aerosols”, J Pharm Tec. 29:199-205, 2013

    Lewerenz J, Hewett SJ, Huang Y, Lambros M, Gout PW, Kalivas PW, Massie A, Smolders I, Methner A, Pergande M, Smith SB, Ganapathy V, Maher P. The Cystine/Glutamate Antiporter System x(c)(-) in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities. . Antioxid Redox Signal, 2012 Aug 3. [Epub ahead of print] PubMed PMID: 22667998.

    Lambros, MP., Parsa, C., Mulamalla, HC., Orlando, R., Lau, B., Pon, D., Chow, M., “Identifying Cell and Molecular Stress After Irradiation in a Three Dimensional (3-D) Model of Oral Mucositis” Biochemical and Biophysica Research Communications, 405:102-106, 2011.

    Wong Beringer, A., Polikandritou Lambros, M., Beringer, P., Johnson D.L., “Suitability of Caspofungin for Prevention of Pulmonary Aspergillosis: Physicochemical Profiling and Nebulizer Choice” Chest, 128:3711-3716, 2005.

    Polikandritou Lambros, M. and Y. E. Rahman "Effect of A Polypeptide on Model Lipid Membranes" Chemistry and Physics of Lipids 131: 63-69, 2004.

    Polikandritou Lambros, M. Abbas, S.A., Dunn T., Raja, T., and Pento, "Targeting Hepatocytes with Liposomal Interferon alpha: "Effect on Metallothionein Gene Induction" Research Communications in Molecular Pathology and Pharmacology, 112:50-58, 2002.

    Abang, A. M., Abbas, S.A., Pham, T., Polikandritou Lambros, M. "A New HPLC Method for Fludarabine and Fludarabine Phosphate Compounded in Liposomes" International Journal of Pharmaceutical Compounding, 5:320-322, 2001

    Polikandritou Lambros, M., Schafer, F., Blackstock, R., and Murphy, J. W., "Liposomes, a Potential Immunoadjuvant and Carrier for a Cryptococcal Vaccine" J. Pharm. Sci., 87:1144-1148, 1998.

    Polikandritou Lambros, M., Sheu, Y. L., and Pereira, H. A., "Interaction of a Synthetic Peptide Based on the Neutrophil-Derived Antimicrobial Protein CAP-37 with Dipalmitoyl-Phosphatidylcholine Membranes", Biochim. Biophys. Acta, 1329:285-290, 1997